St. Luke’s Health has named Augusto “Gus” Sepulveda, MD, MPH, FACP, as the new chief medical officer for its Houston Market and Baylor St. Luke’s Medical Center. The appointment will take effect on March 2, 2026.
Dr. Sepulveda brings nearly three decades of experience in health care leadership and clinical operations. He previously served as chief medical officer at HCA Houston Healthcare Kingwood since May 2025. Before that, he was CMO for HCA Healthcare’s West Florida Division, where he managed clinical quality and patient safety across a network of 17 hospitals and numerous other facilities.
His career also includes leadership roles as associate CMO for HCA Healthcare Gulf Coast Division and as CMO at both HCA Houston Healthcare Northwest and Tomball locations.
“Dr. Sepulveda’s commitment to clinical excellence and patient care is in perfect alignment with CommonSpirit’s mission,” said Simon Payne, MD, MBA, chief medical officer for CommonSpirit’s South Region.“We are confident that his leadership will be a significant asset to the communities we serve in our Houston Market.”
Dr. Sepulveda is board-certified in internal medicine and clinical informatics. He earned his medical degree and Master of Public Health from Ponce Health Sciences University and completed his residency at Hospital Damas, where he was chief resident.
St. Luke’s Health operates eight inpatient hospitals in Greater Houston, including Baylor St. Luke’s Medical Center—a joint venture with Baylor College of Medicine focused on research and teaching. The system has contributed to advancements in cardiovascular care, neurosciences, oncology, transplantation, and more. It employs over 11,000 staff members and providers across the region.
Baylor St. Luke’s Medical Center is an academic hospital with 881 beds offering specialized care in several fields such as cancer treatment through the Dan L Duncan Comprehensive Cancer Center.
Chi Memorial Hospital Georgia is also part of the CommonSpirit Health system according to its official website (https://www.memorial.org/). The hospital group includes three hospitals and 65 care sites focused on providing quality health services (https://www.memorial.org/). Chi Memorial Hospital Georgia has received recognition for its commitment to quality and patient safety from leading organizations (https://www.memorial.org/), aiming to enhance lives through superior care (https://www.memorial.org/). Janelle Reilly serves as president of Chi Memorial Hospital Georgia (https://www.memorial.org/).
